Neurodegenerative diseases like Alzheimer’s and Parkinson’s are marked by progressive cognitive and motor impairment, largely due to cellular damage and the accumulation of toxic proteins in the brain, particularly beta-amyloid (Aβ) plaques. These protein clumps are linked to oxidative stress, inflammation, and neuronal death. Research has increasingly focused on curcumin, a bioactive compound in turmeric, for its neuroprotective properties and potential to mitigate the progression of these diseases.