Nature's Ozempic: Are Berberine and Butyrate Alternative Weight Loss Supplements?
/
Ozempic, Wegovy and Mounjaro have recently gained attention for their effectiveness in weight loss. All of which are GLP-1 (glucagon-like peptide 1) receptor agonists primarily used for managing type 2 diabetes and, more recently, for weight management. These medications mimic the action of GLP-1, a hormone that is produced when we eat, helping to regulate blood sugar, promotes the release of insulin, and reduces appetite, however they can lead to a range of side effects such as nausea, vomiting, digestive issues and nutrient deficiencies. Rapid weight loss may also lead to decreased bone density and muscle mass which is a risk factor of osteoporosis.
Berberine and butyrate are often discussed for their effects on blood sugar regulation and gut health, but could they be a potential alternative to weight loss medications like Ozempic? Here's a breakdown of how these compounds compare and their potential benefits:
Berberine:
Berberine is a herb that is thought to have beneficial effects on blood sugar levels, insulin sensitivity, and lipid metabolism. It activates an enzyme called AMP-activated protein kinase (AMPK), which plays a role in regulating blood sugar, fat storage, and energy balance. This action can help lower blood sugar levels and improve insulin sensitivity.
Benefits:
● Reduces blood sugar levels and HbA1c (a marker for long-term blood sugar control).
● Improves insulin sensitivity.
● May lower cholesterol and triglycerides
While berberine is promising, it may cause gastrointestinal side effects, especially in high doses as it’s also a potent antimicrobial which can impact the gut microbiome.
It's important to note that berberine may interact with certain medications, so it's essential to consult with one of our practitioners before taking it, especially if you are taking other medications or have any underlying health conditions.
Buy Berberine HERE
Butyrate:
Butyrate is a short-chain fatty acid (SCFA) produced by gut bacteria when fibre is fermented in the colon. It's known for its beneficial effects on gut health and metabolism, has anti-inflammatory properties and helps maintain a healthy gut barrier. It can improve insulin sensitivity and support the gut-brain axis, which can influence appetite and weight regulation.
Benefits:
● Improves insulin sensitivity.
● May support weight loss by influencing gut health and metabolism.
● Acts as an anti-inflammatory, potentially reducing the risk of metabolic diseases.
It’s important to note that the effects of butyrate on blood sugar control and weight loss may not be as potent as Ozempic or other GLP-1 receptor agonists. However, it offers a myriad of health benefits beyond supporting gut health.
Both berberine and butyrate show promise as weight loss supplements, particularly for people looking for natural alternatives. However, they do not work in exactly the same way as Ozempic (or other weight loss pharmaceuticals such as Wagovy and Mounjaro), which is designed to mimic a specific hormone involved in appetite regulation. If you're considering these supplements for weight loss, they may offer complementary benefits, particularly for those with metabolic issues.
Buy Butyrate HERE
Further Testing at Body Fabulous
Ultimate Methylation Genetic DNA Test - This test assesses your genetic risk for blood glucose imbalance, eating habits, energy balance and obesity-associated genes which may impact weight management.
Metabolics - Diet & Weight Management DNA Report - This test evaluates genetic factors influencing metabolism, fat storage and weight regulation.
Book a General Advice Call - Speak with our clinical team who can advise on the right testing to help you identify whether your genetics may be impacting weight management.
