You will be asked to fill out a patient form at checkout which will give us more information on your symptoms, current medications and supplement intake to allow us to tailor your protocol to you personally. If you would prefer not to provide this information just write N/A. Ordering as a gift? We require name and gender but other patient details can be marked as N/A. If you wish to purchase multiple tests for people in the same household please add quantity as 1 for each test so that individual patient forms can be completed. You can keep adding multiple tests to the same basket as long as patients reside at the same address. For multiple tests for the same patient you only need to complete the patient form once.

Need it FAST? Order the methylation DNA test via Amazon Prime for Same-Day as well as Overnight delivery in the UK HERE.

Website orders – UK kit delivery via FedEx courier: 2–3 working days.

International delivery – FedEx courier worldwide: 3–4 working days.

The new Ultimate DNA methylation test results format is easy to read with nutritional support included in the lab test so you can choose just the lab results with no support if you prefer.

In ADDITION to your lab results we provide the following methylation support options which are INCLUDED in the package prices:

A) Follow up personalised written report produced by our clinical team. Our team will review your results alongside the patient information you have provided us with and highlight dietary, lifestyle and biohacking advice plus links to a personalised supplement protocol, including specific doses and any further testing required. This document is personalised to you and is 4–5 pages long depending on your results.

B) Follow up 45-minute video call to discuss your results and answer any questions you have. You’ll be sent your DNA results and a link to book a time online. Appointments are usually available next day. Option to upgrade to 60 minutes for an additional £30. Calls include a supplement protocol and are recorded for your private use unless requested otherwise. If the patient is under 18, a parent or guardian must be present.

C) Both Zoom call and written report with personalised next steps (Zoom call is first and written report follows). The written report is longer (6–8 pages) and addresses points discussed during the call.

Once you have ordered via our website you will receive an email notification when your kit has been shipped via FedEx with a tracking number. Please allow 2–3 working days for your kit to arrive in the UK. You can then freepost your sample back via Royal Mail 1st class (UK only). USA, Australia, and Canada orders include prepaid return envelopes. All other international orders require you to arrange return courier postage.

Once we receive your sample, we’ll confirm it via email. Your genotyping takes around 3 weeks. Results will be emailed to you with either a link to book your Zoom call or your written report.

If you opted for a printed copy of your results, you’ll receive a personalised A4 glossy brochure about 2 weeks after your PDF is sent.

How do you test for methylation in the UK? The test is a simple, non-invasive oral sample (cheek swab). The only requirement is to make sure that you do not eat, drink, smoke, chew gum or brush your teeth for 30 minutes prior to collecting the sample. We recommend rinsing your mouth with water 30 minutes before providing your sample to remove any food particles. Any lip balm should be wiped off before providing the sample. Hold the swab head under your tongue for 20 seconds and then the swab head should be rubbed firmly against the inside of each cheek for at least 20 seconds to scrape off as many skin cells as possible. There are no special storage or transport requirements and you can return any day of the week. You can take this test at any time of day, there is no need to stop taking medications or supplements prior to taking your sample. As long as cheek swabs are stored in the dry pouch with the desiccant that is provided with the buccal swab kit, samples remain viable for up to 6 months.

Orders OUTSIDE UK, USA, AUSTRALIA & CANADA - Yes, we can now ship this test all over the world (with the exception of China, India, Mexico, Costa Rica, Iran, Lebanon and Russia). Please select your country at checkout. We use FedEx to deliver our kits, tracking is provided and deliveries usually arrive in 3-4 working days. The test kits are declared as '$2 per kit value' and usually (90% of the time) do not require customs import fees. However, some destination country customs agents may decide (unfortunately, it does seem to be at the discretion of the individual agent) to apply charges, and this is beyond our control and beyond the control of the courier. In the unlikely event this happens, your courier will notify you if an import fee is due before delivering to you. If you are contacted by customs, you should declare the package value as being $2 per test kit which will match the official lab document for a cotton bud swab. We can provide you with a copy of the commercial invoice, if required. We provide approved packaging for the return of the sample, but OUTSIDE UK, USA, AUSTRALIA & CANADA you are responsible for arranging and paying for return postage. All lab reports are provided in English.

Yes — although prepaid return envelopes are provided, you can opt to use your own courier service. If you choose this, you will need to pay for return shipping. We can help provide any customs paperwork needed — just email us.

DNA samples remain viable for up to 6 months when stored in the provided buccal swab pouch.

No — the genetic code is fixed and not affected by illness, infections, medications, food or supplements. Please list any medications or supplements on your patient form. If you're already taking the right supplements for your genes, we’ll confirm that. If anything is missing, we’ll provide recommendations and dosage.

All samples are processed in a CLIA-certified lab and destroyed after 6 months. Your DNA or data is never shared or sold. We use secure, encrypted servers and anonymised barcoding to ensure your privacy and security at every step.

Yes, we provide discounts on methylation testing:

• Order 2 tests — get 5% off — use code ULT5
• Order 3 tests — get 7% off — use code ULT7
• Order 4 or more tests — get 10% off — use code ULT10
• Order 6 or more tests — get 12% off — use code ULT12
• Order 10 or more tests — get 15% off — use code ULT15

Please note all tests must be shipped to the same address.

Yes — we can export your 78 gene variants into an Excel spreadsheet and email this to you if required — order HERE.

What is methylation? When you consume nutrients, your body must convert raw materials into usable forms. Methylation is the key cellular process that acts like billions of tiny switches, turning genes on and off to regulate mood, detoxify hormones, produce energy and support healthy ageing. Because methylation occurs throughout the body, suboptimal methylation can contribute to a wide range of issues.

What does the test tell me? Our 78-gene Genetic Methylation Test looks for variants (SNPs) that can influence how your body processes nutrients and medications. Popularised by Human Biologist and biohacker Gary Brecka, a methylation DNA test highlights predispositions to need more of certain nutrients. Understanding your personal methylation pathways helps you tailor diet, supplements and lifestyle for optimal health.

Yes — preventative healthcare is the future and your DNA never changes, so you only need this test once. Identifying predispositions to require more of specific vitamins or nutrients can help your body perform optimally. A methylation test can be especially insightful for concerns such as fatigue, cardiovascular health, mood, weight management, cholesterol and blood pressure. As a guide, a comprehensive methylation DNA test with expert support is typically around £375. People choose methylation testing to make proactive, personalised choices for their long-term health.

Yes! We’re genetic methylation experts and can help you get the most from your results. We recommend a 45-minute video call to review your data and provide a summary and supplement shopping list. Book below:

The methylation DNA test is a simple, non-invasive cheek swab suitable for any age. Every person’s genetics are unique; children inherit variants from both parents, so they will not have identical gene mutations. Genes are set from birth, so you only need to do this test once in your lifetime and the variant data remains valid for life.

Yes — we ship worldwide on a flat-rate basis. You’ll pay only one delivery charge at checkout per address, regardless of how many kits you order.

• UK, Guernsey, Isle of Man, Jersey: £3.50 per order
• Ireland & Netherlands: £30.00 per order
• Austria, Belgium, Czechia, Croatia, Cyprus, Finland, France, Germany, Greece, Japan, Lithuania, Luxembourg, Malta, Monaco, Serbia, Slovakia, Slovenia, Spain, Sweden: £35.00 per order
• Albania, Argentina, Bahamas, Bosnia and Herzegovina, Brazil, Canada, Colombia, Denmark, Dominican Republic, Ecuador, Estonia, Gibraltar, Guatemala, Hungary, Iceland, Italy, Kenya, Latvia, Macedonia, Mauritania, Mauritius, Moldova, Paraguay, Portugal, Puerto Rico, Romania, Switzerland, Togo, USA: £40.00 per order
• Bulgaria, Jamaica, Kyrgyzstan, Morocco, Poland, Taiwan, Turkey, Zimbabwe: £45.00 per order
• Philippines: £50.00 per order
• Kuwait: £55.00 per order
• Australia, Bahrain, Barbados, Bermuda, Cayman Islands, Chile, Egypt, Hong Kong, Indonesia, Jordan, Kosovo, Malaysia, New Zealand, Norway, Oman, Qatar, Saudi Arabia, Singapore, South Africa, Thailand, UAE: £59.00 per order
• Israel: £65.00 per order

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Gene variants covered: ABCA1 rs1883025, ABCG8 rs6544713, ACE rs4343, ACTN3 rs1815739, ADCY5 rs11708067, ADIPOQ rs17300539, ADIPOQ rs17366568, ADORA2A rs5751876, ADRB2 rs1042713, ADRB3 rs4994, AHCY rs121918608, ALDH2 rs671, AMY1 rs4244372, ANGPTL3 rs10889353, APOA2 rs5082, APOA5 rs12272004, APOA5 rs662799, BCMO1 rs11645428, BDNF rs6265, CD36 rs1761667, CLOCK rs1801260, COL5A1 rs12722, COMT rs4680, CYP17A1 rs743572, CYP19A1 rs10046, CYP19A1 rs2470158, CYP1A2 rs2472300, CYP1B1 rs1056836, CYP2R1 rs10741657, FADS1 rs174547, FTO rs9939609, FUT2 rs601338, GC rs2282679, GC rs4588, GC rs7041, GLUT2 rs5400, GSTP1 rs1695, GSTT1 rs2266633, HFE rs1799945, HFE rs1800562, HLA rs2187668, HLA rs2395182, HLA rs4639334, HLA rs4713586, HLA rs7454108, HLA rs7775228, IL6 rs1800795, IRS1 rs2943641, LEPR rs12405556, LIPC rs1800588, MC4R rs17782313, MCM6 rs4988235, MMP1 rs1799750, MMP3 rs3025058, MTHFD1 rs2236225, MTHFR (A1298C) rs1801131, MTHFR (C677T) rs1801133, MTR rs1805087, MTRR rs1801394, NFIA-AS2 rs1572312, NMB rs1051168, NOS3 rs1799983, NRF2 rs12594956, PEMT rs12325817, PGC1a rs8192678, PPARy2 rs1801282, SLC17A1 rs17342717, SLC30A3 rs11126936, SOD2 rs4880, TCF7L2 rs12255372, TCF7L2 rs7903146, TF rs3811647, TFR2 rs7385804, TMPRSS6 rs4820268, TRPM6 rs11144134, UCP1 rs1800592, UGT2B15 rs1902023, WNT16 rs2707466.

We offer a huge range of testing, so when a member of our genetics team is assigned to review your results they may feel you would benefit from other specific testing such as genetic aging testing, hormones (testosterone / estrogen, cortisol, thyroid levels etc), microbiome, food intolerance, amino acids & homocysteine, mould / toxin testing etc. If any additional testing is required, this will be advised in your Zoom call / written report.

Please note if you have ordered / would like to order the add-on methylation vitamin blood test we will review your DNA results in conjunction with your blood test results to provide you with an accurate review and supplement list. Matching vitamin blood test (UK patients over 18 only) including nurse to your home to take bloods. The benefit of having a blood test and a DNA test at the same time is that we can get your supplement doses exactly correct for your current health.

You cannot purchase this test anywhere else; we are the sole distributors for this specific set of genes and reporting. As the longest-running UK-based DNA specialists, we have been voted Top DNA Testing Service in UK 2025, Biohacking Specialists of the Year 2024, and Health Testing Specialists of the Year 2024–25 by Life Sciences Europe & the Healthcare & Pharmaceutical Awards. Established in 2013, we are the UK’s largest functional medicine clinic.

After purchasing, you will also be able to access the Private Facebook Group, giving you access to health challenges and dozens of useful data sheets and downloads to support you on your health journey.

Unlike other companies a real human being reviews your results! Our Genetic specialists will evaluate your patient intake form to ensure they know more about you before prescribing supplements and dietary changes.