The Ultimate Methylation DNA Test will tell you which supplements and nutrients your body requires for optimal health. Suitable for all ages, our genetic methylation test evaluates key methylation genes as recommended by world renowned biohacker Gary Brecka including MTHFR, COMT, AHCY, MTR, MTRR + ours does 73 more. Receive personalised dietary, supplement and lifestyle recommendations from our expert genetics team. Shipping available worldwide.
OCTOBER Special Offer - Every Ultimate Methylation Test ordered in October comes with a complimentary Histamine DNA Report worth £115. No promo code is needed—this extra report is automatically added to your order.
Why choose our methylation DNA test?

Tailored Nutritional Support
Gain insights into how your body processes key vitamins and minerals, helping you make informed choices about diet and supplements.

Comprehensive DNA Analysis
Explore 78 key gene markers that influence your health. Includes the famous Gary Brecka 5 genes - MTHFR, COMT, AHCY, MTRR and MTR + 73 more.

1-2-1 Support
45 Minute Video Consultations to discuss your results with our Qualified Genetics Team
Our Awards





Order process
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Choose your preferred support package and complete the short patient form at checkout. A flat £3.50 shipping charge is applied regardless of number of tests in the order.
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Kits are shipped same day via FedEx for orders received by 7pm.
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Follow the simple, non-invasive cheek-swab instructions. Returns to the UK are free with a pre-paid envelope.
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You’ll get an e-mail once the lab receives the sample to confirm receipt. Genotyping takes 2-3 weeks; when complete, your PDF results arrive by e-mail. If you have selected a package for Written Report you will receive a personalised report explaining the results, if you have booked a Video Call you will receive a link to book your call with one of our practitioners.
OCTOBER Special Offer - Every Ultimate Methylation Test ordered in October comes with a complimentary Histamine DNA Report worth £115. No promo code is needed—this extra report is automatically added to your order.
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Genetic Methylation DNA - FAQ
Q. How do you support me with my genetic methylation results?
The new Ultimate DNA methylation test results format is easy to read with nutritional support included in the lab test so you can choose just the lab results with no support if you prefer.
In ADDITION to your lab results we provide the following methylation support options which are INCLUDED in the package prices:
A) Follow up personalised written report produced by our clinical team. Our team will review your results alongside the patient information you have provided us with and highlight dietary, lifestyle and biohacking advice plus links to a personalised supplement protocol, including specific doses and any further testing required. This document is personalised to you and is 4–5 pages long depending on your results.
B) Follow up 45-minute video call to discuss your results and answer any questions you have. You’ll be sent your DNA results and a link to book a time online. Appointments are usually available next day. Option to upgrade to 60 minutes for an additional £30. Calls include a supplement protocol and are recorded for your private use unless requested otherwise. If the patient is under 18, a parent or guardian must be present.
C) Both Zoom call and written report with personalised next steps (Zoom call is first and written report follows). The written report is longer (6–8 pages) and addresses points discussed during the call.
Q. I live overseas, can I get this genetic methylation test kit shipped to me?
Yes — we ship worldwide. Please then select your country at checkout. We use FedEx for international orders which typically arrive in 1–4 working days. The kits are declared as $2 value and generally avoid customs fees. If needed, we can provide a commercial invoice. Outside UK/USA/Australia/Canada, customers must arrange and pay for return shipping. All results are provided in English however, in addition, we now offer a translation of 70 of the genes covered in your Ultimate DNA Report in the following languages: French, Spanish, Polish, Portuguese, Indonesian and Arabic.
Q. I currently have a cold / am taking certain medications – will this affect my methylation DNA results?
No — the genetic code is fixed and not affected by illness, infections, medications, food or supplements. Please list any medications or supplements on your patient form. If you're already taking the right supplements for your genes, we’ll confirm that. If anything is missing, we’ll provide recommendations and dosage.
Q. What happens to my DNA after methylation testing?
All samples are processed in a CLIA-certified lab and destroyed after 6 months. Your DNA or data is never shared or sold. We use secure, encrypted servers and anonymised barcoding to ensure your privacy and security at every step.
Q. Can I get a discount for purchasing multiple methylation tests for all my family or friends?
Yes, we provide discounts on methylation testing:
- Order 2 tests — get 5% off — use code ULT5
- Order 3 tests — get 7% off — use code ULT7
- Order 4 or more tests — get 10% off — use code ULT10
- Order 6 or more tests — get 12% off — use code ULT12
- Order 10 or more tests — get 15% off — use code ULT15
Please note all tests must be shipped to the same address.
Q. Can you provide me with my Raw Genetic Methylation Data?
Yes — we can export your 78 gene variants into an Excel spreadsheet and email this to you if required — order HERE.
Q. Should I get my children a genetic methylation DNA test or will they have the same genes as me?
The methylation DNA test is a simple, non-invasive cheek swab suitable for any age. Every person’s genetics are unique; children inherit variants from both parents, so they will not have identical gene mutations. Genes are set from birth, so you only need to do this test once in your lifetime and the variant data remains valid for life.
Q. Do you ship genetic methylation tests to the UK and worldwide?
Yes — we ship worldwide on a flat-rate basis. You’ll pay only one delivery charge at checkout per address, regardless of how many kits you order.
- UK, Guernsey, Isle of Man, Jersey: £3.50 per order
- Ireland & Netherlands: £30.00 per order
- Austria, Belgium, Bulgaria, Croatia, Cyprus, Denmark, Estonia, France, Germany, Gibraltar, Greece, Hungary, Italy, Japan, Lithuania, Luxembourg, Malta, Monaco, Poland, Romania, Serbia, Slovakia, Slovenia, Spain, Sweden, Czechia, Finland, Canada: £35.00 per order
- Albania, Argentina, Bahamas, Bosnia and Herzegovina, Brazil, Colombia, Dominican Republic, Ecuador, Guatemala, Iceland, Kenya, Latvia, Macedonia, Mauritania, Mauritius, Moldova, Paraguay, Portugal, Puerto Rico, Switzerland, Togo, USA: £40.00 per order
- Jamaica, Kyrgyzstan, Morocco, Taiwan, Turkey, Zimbabwe: £45.00 per order
- Australia, Kuwait: £55.00 per order
- Bahrain, Barbados, Bermuda, Cayman Islands, Chile, Egypt, Hong Kong, Indonesia, Israel, Jordan, Kosovo, Malaysia, New Zealand, Norway, Oman, Philippines, Qatar, Saudi Arabia, Singapore, South Africa, Thailand, UAE: £59.00 per order
Q. What genes are covered in the genetic methylation test?
Gene variants covered: ABCA1 rs1883025, ABCG8 rs6544713, ACE rs4343, ACTN3 rs1815739, ADCY5 rs11708067, ADIPOQ rs17300539, ADIPOQ rs17366568, ADORA2A rs5751876, ADRB2 rs1042713, ADRB3 rs4994, AHCY rs121918608, ALDH2 rs671, AMY1 rs4244372, ANGPTL3 rs10889353, APOA2 rs5082, APOA5 rs12272004, APOA5 rs662799, BCMO1 rs11645428, BDNF rs6265, CD36 rs1761667, CLOCK rs1801260, COL5A1 rs12722, COMT rs4680, CYP17A1 rs743572, CYP19A1 rs10046, CYP19A1 rs2470158, CYP1A2 rs2472300, CYP1B1 rs1056836, CYP2R1 rs10741657, FADS1 rs174547, FTO rs9939609, FUT2 rs601338, GC rs2282679, GC rs4588, GC rs7041, GLUT2 rs5400, GSTP1 rs1695, GSTT1 rs2266633, HFE rs1799945, HFE rs1800562, HLA rs2187668, HLA rs2395182, HLA rs4639334, HLA rs4713586, HLA rs7454108, HLA rs7775228, IL6 rs1800795, IRS1 rs2943641, LEPR rs12405556, LIPC rs1800588, MC4R rs17782313, MCM6 rs4988235, MMP1 rs1799750, MMP3 rs3025058, MTHFD1 rs2236225, MTHFR (A1298C) rs1801131, MTHFR (C677T) rs1801133, MTR rs1805087, MTRR rs1801394, NFIA-AS2 rs1572312, NMB rs1051168, NOS3 rs1799983, NRF2 rs12594956, PEMT rs12325817, PGC1a rs8192678, PPARy2 rs1801282, SLC17A1 rs17342717, SLC30A3 rs11126936, SOD2 rs4880, TCF7L2 rs12255372, TCF7L2 rs7903146, TF rs3811647, TFR2 rs7385804, TMPRSS6 rs4820268, TRPM6 rs11144134, UCP1 rs1800592, UGT2B15 rs1902023, WNT16 rs2707466.