The Role of Genetics in Cognitive Decline and Alzheimer’s Disease (APOE)

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The Role of Genetics in Cognitive Decline and Alzheimer’s Disease (APOE)

Cognitive decline and Alzheimer’s disease (AD) are complex conditions influenced by a combination of genetic, environmental and lifestyle factors. Among these, genetic predispositions play a critical role in determining susceptibility, progression and response to interventions. This article explores the connection between genetics and cognitive health, focusing on key genes like Apolipoprotein E (APOE) and others involved in methylation, inflammation, toxicity and neuro (brain) protection.

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A Guide To Methylation DNA Genetic Testing

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A Guide To Methylation DNA Genetic Testing

Methylation DNA testing is very popular now thanks to world renowned biohackers like Gary Brecka from Ultimate Human and the UK’s own Tim Gray.

There are over 20,000 genes in the human body and with many labs offering methylation DNA testing it can be a daunting choice picking which one to order.

Here are some top tips from our Genetics Team to consider prior to purchasing;

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Folinic Acid vs. Methylfolate: Choosing the Right Form of Folate

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Folinic Acid vs. Methylfolate: Choosing the Right Form of Folate

Vitamin B9, commonly referred to as folate, comes in many forms, and choosing the right one can make a significant difference in how your body uses it. You’ve likely seen different names on food packaging or supplements, such as folic acid, folate, folinic acid, and 5-MTHF, but they’re not all created equal.

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What Is Biohacking? A Complete Beginner’s Guide

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What Is Biohacking? A Complete Beginner’s Guide

Biohacking is the practice of using science, technology, and lifestyle interventions to optimise health, performance, and well-being. Often viewed as the art and science of "hacking" biology, biohacking combines principles from fields such as nutrition, neuroscience, genetics, and exercise physiology to help people improve their physical and mental health. Biohacking can be as simple as taking supplements to enhance cognitive performance or as complex as implanting devices to monitor physiological responses.

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MTHFR Gene: Variants, Symptoms & Testing

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MTHFR Gene: Variants, Symptoms & Testing

Order MTHFR Testing HERE

Understanding the MTHFR Gene: Functions, Variants, and Implications

The MTHFR (Methylenetetrahydrofolate Reductase) gene is a key player in a critical metabolic process known as methylation, which is essential for DNA synthesis, repair, and overall cellular function. The enzyme produced by the MTHFR gene converts 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, the active form of folate. This active folate is crucial for converting homocysteine into methionine, an amino acid necessary for many biological functions, including the synthesis of proteins and neurotransmitters.

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Neurodiversity: The Role of Genetics

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Neurodiversity: The Role of Genetics

Neurodiversity is a concept that recognises and embraces the variety of ways the brain can function and process information. It celebrates neurological differences, such as autism, ADHD, dyslexia and other cognitive variations, as part of human diversity rather than viewing them as disorders. Genetic factors play a critical role in shaping the brain's development and function, and understanding the genetic basis of neurodiversity can offer valuable insights into individual strengths, challenges and potential interventions. This article explores key genes that influence neurological development and cognitive functions. Understanding these genes can empower individuals and their loved ones to make informed choices about their health, optimise brain function and explore personalised strategies for support in terms of nutrition, lifestyle and supplementation, which can quite literally be life changing for some individuals.

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